China (Mainland)
High Quality Topiramate CAS NO.97240-79-4
- FOB Price: USD: 1.00-1.00 /Gram Get Latest Price
- Min.Order: 1 Gram
- Payment Terms: L/C,D/A,D/P,T/T,MoneyGram
- Available Specifications:
1(1-2)Gram
- Product Details
Keywords
- 97240-79-4
- Topiramate
- Topiramate Price
Quick Details
- ProName: High Quality Topiramate
- CasNo: 97240-79-4
- Molecular Formula: C12H21NO8S
- Appearance: White powder
- Application: pharmaceutical intermediates
- DeliveryTime: Qingdao Port
- PackAge: 1kg or 25Kg drum
- Port: QIngdao Port
- ProductionCapacity: 3000 Metric Ton/Year
- Purity: 98% HPLC
- Storage: Store in dry, dark and ventilated plac...
- Transportation: By air or by sea. Prompt delivery
- LimitNum: 1 Gram
- Moisture Content: See data sheet
- Samples: Available
Superiority
We promise our customer following items
1.Reasonable price:
2.Low moq:No worry about the low moq, our moq is 1 gram or lower.
3.Good and efficient service,Fast Delivery
4.Super-good quality
Details
Description
Topiramate is an anticonvulsant that antagonizes GluR5 receptors (IC50 = 0.46 μM) and acts as a positive allosteric modulator of
GABAA receptor-mediated currents. This compound inhibits Nav channels (IC50 = 48.9 μM) and inhibits L-type Ca2+ channels.
Topiramate inhibits carbonic anhydrase (CA) (Ki values are 0.1 and 0.2 μM in rat CA II and CA IV, respectively).
Specifications
| Items | Specifications | Results |
| Appearance | White to off-white powder, Freely soluble in dichloromethane | White powder, Freely soluble in dichloromethane |
| Identification | Infared Absorption | Complies |
| The retention time of the major peak in the chromatogram of the Assay prepration corresponds to that in the chromatogram of the standard preparation, as obtained in the assay | complies | |
| Specific rotation | Between -28.6°and -35.0°, measured at 20° | -32.8° |
| Water | not more than 0.5% | 0.12% |
| residue on ignition | not more than 0.2% | 0.11% |
| Heavy metals | not more than 0.001% | complies |
| related compounds by HPLC(Test1) | Fructose not more than 0.3% Compound A not more than 0.3% Other individual impurity not more than 0.1% Total impurities not more than 0.5% |
Fructose: 0.03% Compound A:0.04% individual impurity Total impurities: 0.07% |
| Particle size | 90% less than 350 microns | complies |
| Limit of sulfamate and sulfate | Sulfamate ion not more than 0.10% Sulfate ion not more than 0.10% | complies |
| Residual Solvent | Methylene Chloride not more than 250μg/g | not detected |
| Acetone not mor than 2500μg/g | ||
| Isopropanol not more than 5000μg/g | ||
| Ethanenitrile not more than 400μg/g | ||
| n-hexane not more than 290μg/g | ||
| Ethyl Acetate not more than 2500μg/g | ||
| Pyridine not more than 100μg/g | ||
| Assay | Topiramate contains not less than 98.0% and not more than the equivalent of 102.0% of C12H21NO8S, calculated with reference to the Anhydrous Basis | 99.80% |
| Conclustion | The material complies with respect to USP35 | |
Usage
1) Topiramate is used to treat epilepsy in children and adults, and it was originally used as an anticonvulsant.
In children, it is indicated for the treatment of Lennox-Gastaut syndrome, a disorder that causes seizures and
developmental delay.
2) This drug has been investigated for use in treating alcoholism
especially to reduce binge eating.
3) This drug is also widely used to treat migraines due to the effect it has on the blood vessels in the brain
4) The drug is also used in clinical trials to treat post traumatic stress disorder
5) And recently. clinical reports indicate that it may have mood stabilizing properties.
25kg carton drum (32cm*58cm)or 1kg foil bag (10cm*15cm) or by request of clients
Transit could be DHL,UPS,TNT,EMS,Fedex,and so on.
For mass orders, it will be delivered by air or sea.
Depending on your location, please allow 1-5 business days for your order to arrive.
For small order, please expect 3-7 days by UPS DHL EMS.
For mass order, please allow 5-8 days by Air, 15-30 days by Sea.
