High quality apixaban CAS NO.503612-47-3
- FOB Price: USD: 1.00-1.00 /Metric Ton Get Latest Price
- Min.Order: 1 Kilogram
- Payment Terms: L/C,D/A,D/P,T/T,Other
- Available Specifications:
1(1-2)Metric Ton
- Product Details
Keywords
- apixaban
- 503612-47-3
- apixaban Price
Quick Details
- ProName: High quality apixaban
- CasNo: 503612-47-3
- Molecular Formula: C25H25N5O4
- Appearance: White powder
- Application: pharmaceutical intermediates
- DeliveryTime: WIthin 2 days
- PackAge: 25KG/DRUM
- Port: Qingdao Port
- ProductionCapacity: 3000 Metric Ton/Month
- Purity: 99%
- Storage: Store in dry dark and ventilated place
- Transportation: By express,By Air or by sea
- LimitNum: 1 Kilogram
Superiority
Details
Apixaban is a highly selective, reversible, and direct inhibitor of Human Factor X and Rabbit Factor X with Ki of 0.08 nM and 0.17 nM, respectively. Apixaban exhibits a high degree of potency, selectivity, and efficacy on Factor X with Ki of 0.08 nM and 0.17 nM for Human Factor X and Rabbit Factor X, respectively. In vitro, Apixaban prolongs the clotting times of normal human plasma with theconcentrations (EC2x) of 3.6 μM, 0.37 μM, 7.4 μM, and 0.4 μM, which are required respectively to double the prothrombin time (PT),modified prothrombin time (mPT), activated partial thromboplastin time (APTT) and HepTest. Besides, Apixaban shows the highestpotency in human and rabbit plasma, but less potency in rat and dog plasma in both the PT and APTT assays
Name |
Apixaban |
Synonyms |
1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide |
Brand |
Salus |
Molecular Formula |
C25H25N5O4 |
Molecular Weight |
459.50 |
CAS Registry Number |
503612-47-3 |
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