High Quality L-Lysine homopolymer hydrobromide CAS NO.25988-63-0
- FOB Price: USD: 1.00-1.00 /Gram Get Latest Price
- Min.Order: 1 Gram
- Payment Terms: L/C,D/A,D/P,T/T,
- Available Specifications:
1(1-2)Gram
- Product Details
Keywords
- 25988-63-0
- L-Lysine homopolymer hydrobromide
- L-Lysine homopolymer hydrobromide Price
Quick Details
- ProName: High Quality L-Lysine homopolymer hydr...
- CasNo: 25988-63-0
- Molecular Formula: C6H12N2OHBr)n+H2O
- Appearance: White powder
- Application: pharmaceutical intermediates
- DeliveryTime: Qingdao Port
- PackAge: 1kg or 25Kg drum
- Port: QIngdao Port
- ProductionCapacity: 3000 Metric Ton/Year
- Purity: 98% HPLC
- Storage: Store in dry, dark and ventilated plac...
- Transportation: By air or by sea. Prompt delivery
- LimitNum: 1 Gram
- Moisture Content: See data sheet
- Samples: Available
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2.Low moq:No worry about the low moq, our moq is 1 gram or lower.
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Details
Product Details
Poly-L-lysine is a positively charged amino acid polymer. There is approximately one HBr perlysine residue. The HBr allows the poly-L-lysine to be a crystalline solid and soluble in water. To remove the HBr, solubilize it in a neutral buffer and dialyze to remove the salts.
None of the poly-L-lysine products are exposed to trifluoroacetic acid (TFA). They are dialyzed to remove monomer, dimer, trimer, (i.e. short chains) and then analyzed by thin layer- chromatography (TLC) to determine the effectiveness of this process.
Purification of high or low molecular weight poly-L-lysines by size exclusion chromatography is not very effective. Some success has been achieved using succinylated derivatives. A more traditional method for fractionating polymers, such as dialysis with membranes of suitable molecular weight cut-off, is suggested.
A method for molecular weight determination by viscosity has been published.
In order to determine the molecular weight by SEC-LALLS, it is necessary to succinylate the poly-L-lysine. If this is not done, the product will form aggregates.
Applications
for poly-L-lysine include the promotion of cell adhesion to
solid substrates,conjugation to methotrexate for increased drug transport, microencapsulation of islets, cell microencapsulation technology,microarray glass slide coating,and chromosomal preparations.
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