offer sell cas Melanotan2 melanotan ii Melanotan-II(MT2) hot sale CAS NO.121062-08-6

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Quick Details

ProName: offer sell cas Melanotan2 melanotan i...
CasNo: 121062-08-6
Molecular Formula: C50H71N15O10
Appearance: White powder
Application: nutritional supplement.
DeliveryTime: Within 2 days
PackAge: 10mg/vial
Port: Qingdao Port
ProductionCapacity: 9999999 Milligram /Day
Purity: 99%
Storage: -20
Transportation: by air
LimitNum: 1 Metric Ton
Related Substances: 0
Residue on Ignition: 0
Heavy Metal: NA
Valid Period: 2 year
Email: info@sigmachemical.com.cn

Superiority

offer sell cas Melanotan2 melanotan ii Melanotan-II(MT2) hot sale

Description Melanotan II is a synthetic analogue of the melanocortin peptide hormone alpha-melanocyte stimulating hormone (α-MSH) that occurs naturally. In usage, Melanotan II has been revealed to have aphrodisiac and melanogenesis (tanning) effects that have been subjected to clinical trials and preliminary studies. The compound is a cyclic lactam analogue of α-MSH that has an amino sequence named MTII (Ac-Nle-c[Asp-His-D-Phe-Arg-Trp-Lys]-NH2). Notably, no government drug regulatory agency across the world had approved for the use of any compound incorporating the Melanotan II peptide by 2010

Historical Development Melanotan II was first developed at the University of Arizona. Various studies conducted at the institution confirmed that the best defence against skin cancer was melanin activated in the skin, a tan. The researchers assumed that an effective procedure to reduce the rates of skin cancer in individuals would be by inducing the body’s natural pigmentary system to produce a tan that would be protective before exposure to UV. Melanogenesis is a process by which the skin’s pigment cells (melanocytes) produce the hormone α-MSH naturally causes the skin's pigment (melanin).

After numerous clinical trials by administration of the endogenous hormone to the body, the scientists found that though it appeared to work, α-MSH had a very short half-life in the body to be practical as a therapeutic drug. Therefore, they opted to look for a more stable and potent alternative that would be more practical. Subsequently, after numerous trials, they developed Melanotan I and after that Melanotan II.

Uses Malanotan II is used for tanning of the skin and producing of erections in men with erectile dysfunction when administered as a shot under the skin. Malanotan II is safe when used under strict medical supervision for treating erectile dysfunction. However, it may cause stomach cramps, tiredness, nausea, spontaneous erections of the penis, and darkened skin.

Controversy Melanotan II is widely sold online and in beauty salons as well as gyms as melanotan in their marketing. These products purport to contain the same chemical composition as afamelanotide. These products have been declared illegal and do not have the same chemical components as Melanotan II. As such, countries issues warnings against their use.

Melanotan II Basic information

Description Historical Development Uses Controversy

Product Name:	Melanotan II
Synonyms:	AC-NLE-ASP-HIS-D-PHE-ARG-TRP-LYS-NH2, ASP5-LYS10, CYCLIC LACTAM;AC-NLE-C[+ASP-HIS-DPHE-ARG-TRP-LYS]-NH2;[ACETYL-NLE4, ASP5, D-PHE7, LYS10]-ALPHA-MELANOCYTE STIMULATING HORMONE (4-10) AMIDE;[ACETYL-NLE4, ASP5, D-PHE7, LYS10]-ALPHA-MSH (4-10) AMIDE;(ACETYL-NLE4,ASP5,D-PHE7,LYS10)-CYCLO-ALPHA-MSH (4-10) AMIDE ACETATE SALT;MELANOTAN II;[N-ACETYL-NLE4,ASP5,D-PHE7,LYS10]-ALPHA-MSH (4-10) AMIDE ASP5-LYS10, CYCLIC LACTAM;MTII
CAS:	121062-08-6
MF:	C50H69N15O9
MW:	1024.18
EINECS:	1308068-626-2
Product Categories:	-;Amino Acid Derivatives;Peptides;Peptide;Melanocortin receptor
Mol File:	121062-08-6.mol

Melanotan II Chemical Properties

density	1.43
RTECS	OL4225000
storage temp.	−20°C
solubility	H₂O: 5 mg/mL, soluble
form	solid
color	white
InChIKey	JDKLPDJLXHXHNV-MFVUMRCOSA-N
CAS DataBase Reference	121062-08-6(CAS DataBase Reference)

Safety Information

Hazard Codes	Xn
Risk Statements	22
WGK Germany	3

Details

Product Description

Melanotan II (CAS NO.121062-08-6) was first synthesized at the University of Arizona. Researchers decided to find a more potent and stable alternative, one that would be more practical to defenses against skin cancer.The researchers headed by Victor Hruby, found a peptide, [Nle4, D-Phe7]-α-MSH, that was approximately 1,000 times more potent than natural α-MSH after synthesizing and screening hundreds of molecules. They dubbed this new peptide, "Melanotan" (later Melanotan I, now known as afamelanotide). They subsequently developed another analog, Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2), which they named "Melanotan ⅡAcetate". Since their discovery, numerous studies dating back to the mid-1980s have found no obvious toxic effects of the Melanotan peptides. The scientists hoped to use Melanotan peptides to combat melanoma by stimulating the body's natural tanning mechanism to create a tan without first needing exposure to harmful levels of UV radiation. This in turn, they hypothesized, could reduce the potential for skin damage that can eventually lead to skin cancer.

Certification of Analysis

ITEM	SPECIFICATION	RESULTS
Appearance	Fine powder	Complies
Color	White	Complies
Odor&Taste	Characteristic	Complies
Assay	≥99%	99.13%
Heavy Metals	≤10ppm	Complies
Pb	≤2ppm	Complies
As	≤2ppm	Complies
Hg	≤1ppm	Complies
Cadmium	≤1ppm	Complies
Sulphates	≤300ppm	Complies
Ammonium	≤200ppm	Complies
Iron	≤10ppm	Complies
Microbiological Control
Total plate count	≤1000CFU/G	Complies
Yeast & mold	≤100 CFU /G	Complies
Total coli forms	≤100 CFU /G	Complies
E.coli	Negative	Negative
Salmonella	Negative	Negative

Function&Application

It's a kind of nutritional supplement. (2)It can improve the aerobic metabolism of the muscle and greatly enhance muscle strength and endurance from diet alone. (3)It can be used as nutrition enhancer.(4)It's one of the most popular and effective nutritional supplements as well as the indispensable product for bodybuilders. (5 It's also widely used by other athletes, such as football players, basketball players and so on.

offer sell cas Melanotan2 melanotan ii Melanotan-II(MT2) hot sale