High Quality Side chain for meropenem CAS NO.96034-64-9

 Qingdao Sigma Chemical Ltd is is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, peptide,Nootropis etc API, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.

 

Our Laboratory is located in shandong province. There are 15 experts in our research team. Talented personnel and well-equipped laboratory makes rigorous and professional quality control possible. Lyphar Biotech is equipped with various detection devices, such as HPLC, GC, Spectrophotometer, AAS, Polarimeter, Auto titrators, BOD Incubators, COD Incubators, Melting point apparatus and so on.

 

The aim of QDSIGMA is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.

 

QDSIGMA has become the "Top 500 Chinese manufacturing companies","Top 20 of global chemical sales".QDSIGMA has 21 subsidiaries and holding companies.

Product name: Side chain for MeropenemSynonyms: (2S,4S)-2-Dimethylcarbamoyl-4-Mercapto-Pyrrolidine-1-Carboxylic Acid 4-Nitro-Benzyl Ester Molecular 

Formular:C15H19N3O5S

Molecular Weight: 353.39

CAS NO.: 96034-64-9

Specifications:

Appearance: Light yellow or almost white crystalline powder

Assay : 97.0%min(HPLC)

Loss on drying: 1.0% max

Packing: 25kg/cardboard drum

Usage: Meropenem intermediate

Storage: Refrigeration, seal up and keep away from light. Must be stored in low-temperature(-8.0~+10)

1. Introduction 

Meropenem is an ultra-broad-spectrum injectable antibiotic used to treat a wide variety of infections. It is a beta-lactam and belongs to the subgroup ofcarbapenem, similar to imipenem and ertapenem. Meropenem was originally developed by Dainippon Sumitomo Pharma.It gained US FDA approval in July 1996. It penetrates well into many tissues and body fluids including thecerebrospinal fluid, bile, heart valves, lung, and peritoneal fluid.

2.Indications

The spectrum of action includes many Gram-positive and Gram-negative bacteria (including Pseudomonas) and anaerobic bacteria. The overall spectrum is similar to that of imipenem, although meropenem is more active againstEnterobacteriaceae and less active against Gram-positive bacteria. It is also very resistant to extended-spectrum beta lactamases but may be more susceptible to metallo-beta-lactamases. Meropenem is frequently given in the treatment of febrile neutropenia. This condition frequently occurs in patients withhematological malignancies and cancer patients receiving anticancer drugs that cause bone marrow suppression. It is approved for complicated skin and skin structure infections, complicated intra-abdominal infections and bacterial meningitis

3.Specification