China (Mainland)
High quality AICAR with best price 2627-69-2 CAS NO.2627-69-2
- FOB Price: USD: 1.00-1.00 /Metric Ton Get Latest Price
- Min.Order: 1 Kilogram
- Payment Terms: L/C,D/A,D/P,T/T,Other
- Available Specifications:
1(1-10)Metric Ton
- Product Details
Keywords
- AICAR
- 2627-69-2
- AICAR Price
Quick Details
- ProName: High quality AICAR with best price 262...
- CasNo: 2627-69-2
- Molecular Formula: C9H14N4O5
- Appearance: White powder
- Application: pharmaceutical intermediates
- DeliveryTime: WIthin 2 days
- PackAge: 25KG/DRUM
- Port: Qingdao Port
- ProductionCapacity: 3000 Metric Ton/Month
- Purity: 99%
- Storage: Store in dry dark and ventilated place
- Transportation: By express,By Air or by sea
- LimitNum: 1 Kilogram
- Moisture Content: Appearance Off-white powder
- Impurity: NA
- Application: Sports Supplement
Superiority
Details
Name: Aicar
CAS No: 2627-69-2
Molecular Formular: C9H14N4O5
Molecular Weight: 258.2
Appearance: Off-white powder
Chemical name: 5-Aminoimidazole-4-carboxamide ribonucleotide
Package size: 1g/5g/10g/100g or as per customers' requirement
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Name: Aicar
CAS No: 2627-69-2
Molecular Formular: C9H14N4O5
Molecular Weight: 258.2
Appearance: Off-white powder
Chemical name: 5-Aminoimidazole-4-carboxamide ribonucleotide
Package size: 1g/5g/10g/100g or as per customers' requirements
Uses
AICAR (AICA-Riboside) strongly inhibits the transcription of PPARα and the coactivation of PPAR&alpha. In adipocyte studies it has been shown to antagonize lipolysis induced by isoprenaline and has been suggested for use in kinase cascade research. Additionally, research indicates that AICAR blocks the differentiation of 3T3-L1 (sc-2243) adipocytes. Studies demonstrate that AICAR can mimic the activity of insulin (sc-211647) by activating AMPK (AMP-activated protein kinase), and affecting the expression of PEPCK-M (PEPCK) and glucose-6-phosphatase (G6Pase). The 5-aminoimidazole-4-carboxamide ribonucleoside (ZMP) is the monophosphorylated derivative of AICA-Riboside, and it can serve as the substrate for the aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC).
Application
(1) Applied in phamaceutical field, it is used as phamaceutical raw material to treat injuries from fall, infectious hepatitis and epidemic cerebrospinal meningitis.
(2) Applied in healthcare field, it is used in the health products to nourish brain, protect liver and improve sleep quality.
(3) Applied in comestics, it is used to promote skin metabolism and make skin more tender and firm.
