High quality Amphotericin B CAS NO.1397-89-3
- FOB Price: USD: 1.00-1.00 /Metric Ton Get Latest Price
- Min.Order: 1 Kilogram
- Payment Terms: L/C,D/A,D/P,T/T,Other
- Available Specifications:
1(1-10)Metric Ton
- Product Details
Keywords
- Amphotericin B
- 1397-89-3
- Amphotericin B Price
Quick Details
- ProName: High quality Amphotericin B
- CasNo: 1397-89-3
- Molecular Formula: C47H73NO17
- Appearance: White powder
- Application: pharmaceutical intermediates
- DeliveryTime: WIthin 2 days
- PackAge: 25KG/DRUM
- Port: Qingdao Port
- ProductionCapacity: 3000 Metric Ton/Month
- Purity: 99%
- Storage: Store in dry dark and ventilated place
- Transportation: By express,By Air or by sea
- LimitNum: 1 Kilogram
- Moisture Content: NA
- Impurity: NA
- Email: info@sigmachemical.com.cn
Superiority
Details
Introduction
Amphotericin B (Fungilin, Fungizone, Abelcet, AmBisome, Fungisome, Amphocil, Amphotec) is a polyene antifungal drug, often
used intravenously for systemic fungal infections. It was originally extracted from Streptomyces nodosus,a
filamentousbacterium, in 1955 at the Squibb Institute for Medical Research from cultures of an undescribed streptomycete
isolated from the soil collected in the Orinoco River region of Venezuela. Its name originates from the
chemical's amphoteric properties. Two amphotericins, amphotericin A and amphotericin B are known, but only B is used
clinically, because it is significantly more activein vivo. Amphotericin A is almost identical to amphotericin B (having a double
C=C bond between the 27th and 28th carbons), but has little antifungal activity.
Currently, the drug is available as plain amphotericin B, as a cholesteryl sulfate complex (ABCD), as a lipid complex (ABLC),
and as a liposomal formulation (LAmB). The latter formulations have been developed to improve tolerability for the patient, but
may show considerably different pharmacokinetic characteristics compared to plain amphotericin B.
Specification
Items |
Specifications |
Results |
Appearance |
Yellow to orange powder,odorless or practically so. |
Yellow powder |
Solubility |
Insoluble in water and in ether,slightly soluble in methanol |
Conforms |
Identification A:(UV) |
Conforms to standard;absorbance in the range of 240nm to 320nm |
Conforms |
Identification B:(UV/Vis) |
Conforms to standard;absorbance in the range of 320nm to 400nm |
Conforms |
Loss on drying |
Not more than 5.0% |
0.4% |
Residue On Ignition |
Not more than 3.0% |
0.4% |
Limit of amphotericin A |
Not more than 15% |
Not detected |
Assay(microbial) |
Not less than 750µg/mg calculated on the dried basis |
919µg/mg |
Microbial Limits: |
|
|
Total Aerobic Count |
Not more than 100CFU/gram |
0CFU/gram |
Salmonella Species |
Negative |
Conforms |
Escherichia Coli |
Negative |
Conforms |
Residual solvents |
|
|
Ethanol |
Not more than 5000ppm |
1000ppm |
Acetone |
Not more than 5000ppm |
1410ppm
|
25kg/drum or according client's demands.
Transit could be DHL,UPS,TNT,EMS,Fedex,and so on.
For mass orders, it will be delivered by air or sea.
Depending on your location, please allow 1-5 business days for your order to arrive.
For small order, please expect 3-7 days by UPS DHL EMS.
For mass order, please allow 5-8 days by Air, 15-30 days by Sea.
1.Cooperate with research institutions, we strictly control the process from raw material to finished product.
2.The customer comes first, we provide reasonable price, high quality product and prompt shipment.
3.We can send the goods to your delivery address directly. It is relatively safe and fast. We have ready goods in stock.
4.Quick and clear response to customers questions.
Warm after sale service, we will help to solve the problems in your usage.
5.We could make our price discount if you place a substantial order with us.
QDOCEAN Import And Export Co., Ltd is is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc.
The aim of QDOCEAN is a quality policy that "Elements in the system all have been satisfied, Personnel has been trained; Every batch of material is checked, Each procedure guarantees the quality; Every bag of our products is top grade, Service is thoughtful all the time, quality and reputation to increase market share and promote enterprise development. The quality, colors and forms of our products have reached a high level in related chemical industry, which relies on characteristic and advanced processing technology and it has gained a high and reliable reputation from customers at both quality and services.
QDOCEAN has become the "Top 500 Chinese manufacturing companies","Top 20 of global agrochemical sales".QDOCEAN has 21 subsidiaries and holding companies.